CDS

Accession Number TCMCG025C36879
gbkey CDS
Protein Id XP_021641237.1
Location complement(join(355811..356024,356264..356384,377253..377324,383770..383841,384381..384459,385032..385070,393697..393796,393938..393990,415168..415297,416902..416936,428562..428666,429154..429243,450862..450936,470558..470686,470817..470996,473353..473436,473893..474009,474102..474174,474263..474384,474493..474615,474916..474988,475126..475304,476744..477028))
Gene LOC110636028
GeneID 110636028
Organism Hevea brasiliensis

Protein

Length 849aa
Molecule type protein
Topology linear
Data_file_division PLN
dblink BioProject:PRJNA394253
db_source XM_021785545.1
Definition DNA topoisomerase 3-alpha isoform X5 [Hevea brasiliensis]

EGGNOG-MAPPER Annotation

COG_category L
Description Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand
KEGG_TC -
KEGG_Module M00414        [VIEW IN KEGG]
KEGG_Reaction -
KEGG_rclass -
BRITE ko00000        [VIEW IN KEGG]
ko00001        [VIEW IN KEGG]
ko00002        [VIEW IN KEGG]
ko01000        [VIEW IN KEGG]
ko03032        [VIEW IN KEGG]
ko03400        [VIEW IN KEGG]
KEGG_ko ko:K03165        [VIEW IN KEGG]
EC 5.99.1.2        [VIEW IN KEGG]        [VIEW IN INGREDIENT]
KEGG_Pathway ko03440        [VIEW IN KEGG]
ko03460        [VIEW IN KEGG]
map03440        [VIEW IN KEGG]
map03460        [VIEW IN KEGG]
GOs GO:0000003        [VIEW IN EMBL-EBI]
GO:0003674        [VIEW IN EMBL-EBI]
GO:0003676        [VIEW IN EMBL-EBI]
GO:0003677        [VIEW IN EMBL-EBI]
GO:0003824        [VIEW IN EMBL-EBI]
GO:0003916        [VIEW IN EMBL-EBI]
GO:0003917        [VIEW IN EMBL-EBI]
GO:0005488        [VIEW IN EMBL-EBI]
GO:0005575        [VIEW IN EMBL-EBI]
GO:0005622        [VIEW IN EMBL-EBI]
GO:0005623        [VIEW IN EMBL-EBI]
GO:0005634        [VIEW IN EMBL-EBI]
GO:0005654        [VIEW IN EMBL-EBI]
GO:0006139        [VIEW IN EMBL-EBI]
GO:0006259        [VIEW IN EMBL-EBI]
GO:0006260        [VIEW IN EMBL-EBI]
GO:0006265        [VIEW IN EMBL-EBI]
GO:0006725        [VIEW IN EMBL-EBI]
GO:0006807        [VIEW IN EMBL-EBI]
GO:0006996        [VIEW IN EMBL-EBI]
GO:0007049        [VIEW IN EMBL-EBI]
GO:0008150        [VIEW IN EMBL-EBI]
GO:0008152        [VIEW IN EMBL-EBI]
GO:0009058        [VIEW IN EMBL-EBI]
GO:0009059        [VIEW IN EMBL-EBI]
GO:0009987        [VIEW IN EMBL-EBI]
GO:0016043        [VIEW IN EMBL-EBI]
GO:0016604        [VIEW IN EMBL-EBI]
GO:0016605        [VIEW IN EMBL-EBI]
GO:0016853        [VIEW IN EMBL-EBI]
GO:0022414        [VIEW IN EMBL-EBI]
GO:0031974        [VIEW IN EMBL-EBI]
GO:0031981        [VIEW IN EMBL-EBI]
GO:0034641        [VIEW IN EMBL-EBI]
GO:0034645        [VIEW IN EMBL-EBI]
GO:0043170        [VIEW IN EMBL-EBI]
GO:0043226        [VIEW IN EMBL-EBI]
GO:0043227        [VIEW IN EMBL-EBI]
GO:0043229        [VIEW IN EMBL-EBI]
GO:0043231        [VIEW IN EMBL-EBI]
GO:0043233        [VIEW IN EMBL-EBI]
GO:0044237        [VIEW IN EMBL-EBI]
GO:0044238        [VIEW IN EMBL-EBI]
GO:0044249        [VIEW IN EMBL-EBI]
GO:0044260        [VIEW IN EMBL-EBI]
GO:0044422        [VIEW IN EMBL-EBI]
GO:0044424        [VIEW IN EMBL-EBI]
GO:0044428        [VIEW IN EMBL-EBI]
GO:0044446        [VIEW IN EMBL-EBI]
GO:0044451        [VIEW IN EMBL-EBI]
GO:0044464        [VIEW IN EMBL-EBI]
GO:0046483        [VIEW IN EMBL-EBI]
GO:0051276        [VIEW IN EMBL-EBI]
GO:0051321        [VIEW IN EMBL-EBI]
GO:0070013        [VIEW IN EMBL-EBI]
GO:0071103        [VIEW IN EMBL-EBI]
GO:0071704        [VIEW IN EMBL-EBI]
GO:0071840        [VIEW IN EMBL-EBI]
GO:0090304        [VIEW IN EMBL-EBI]
GO:0097159        [VIEW IN EMBL-EBI]
GO:0140097        [VIEW IN EMBL-EBI]
GO:1901360        [VIEW IN EMBL-EBI]
GO:1901363        [VIEW IN EMBL-EBI]
GO:1901576        [VIEW IN EMBL-EBI]

Sequence

CDS:  
ATGATCAACGTCTTGAACGTCGCGGAGAAGCCGTCTGTAGCGAAATCGGTGGCCACCATACTCTCAAGGAACCAGCAGCATGGGATGAGAGTTAGGGACGGGCGGTCCCGCTACAACAAGATCTTCGAGTTCAACTACGTGATCAACGGGCAGCCATGCCATATGCTAGTGACTTCCGTCACTGGTCATCTCATGGAGCTCGAGTTCGAGGATCGCTTCCGCAAGTGGCATTCTTGCGATCCCACCGATCTCTACCATGCCCCCGTCCGTAAATTCGTCCCTGAGGACAAGATAGATATCAAAAGGACATTGGAGGAGGAAGCAAGAAGGTGCCAGTGGCTTATTCTGTGGCTTGATTGTGATAGAGAGGGAGAAAACATTGCATTTGAAGTGATGGATGTTTGTGGAGCAGCAAATCGCCACCTTACTATATGGAGGGCTCGCTTTTCTGCATTAATTGACAGGGAAATTCATGAGGCAGCCCAAAATCTTGTTTCTCCTAATCAGTGGTTTTCTGATGCTGTGGATGCTAGGCAAGAAATTGATCTCCGCATTGGTGCGTCTTTCACAAGGTTTCAAACCATGCTGCTGAGAGATAAGTTTGTTATTGGTTCTGCTCAAGATGACAGAAATCTTGTTCTAAGTTATGGGCCTTGTCAGTTCCCTACGCTTGGCTTTATTGTCGAACGTTATTGGGAGATACAATCACATGAGCCAGAAGAGTTTTGGACTATTAATTGTTCTCACACAACAGATGAAGGCATTGCAACCTTCAGTTGGATGCGTGGACATCTTTTTGATTACACTTCTGCTGTTATACTTTATGAAATGTGTGTTCAGGAACCAGCTGCGACTGTAACAAAGGTTCATCAGCAGGAGAAGCGAAAGTACCCTCCGCATCCTCTGAGTACAATTGAGCTTGAAAAACGTGCCTCAAGATATTTCAGAATGAGTTCTGAACAGACCATGAAAGTGGCAGAAGATCTATACCAAGCTGGTTTCATTAGTTATCCTCGTACAGAGACCGATGGCTTCTCTAGCAGGACTGATTTGCATACAATTGTGCGAGAACAACAGGAGCATCCGGTATGGGGTTCATATGCTCAACGACTCTTAGATCCTGGAACAGGATTATGGAGAAATCCCAGCAGTGGTGGACACGATGACAAAGCACATCCTCCCATTCATCCAACAAAGTTTTCTGCTGGTGAAATTGGATGGAGTCAAGATCATCATAGAGTGTATGAGTTGGTTGTTCGCCATTTTCTGGCATGTGTTTCTCAACCAGCTGTTGGGGCTGAAACTATTGTTGAAATTGATATTGCTGGTGAACAGTTTTCTGCATCAGGGAGGGTGATATTAGTTAAAAATTACTTGGATGTTTACCATTTTGAATCATGGGGTGGTTTAATGATTCCAACCTATCTTCAAGGCCAACAGTTTATCCCAACCACTCTAACTCTTGATTCAGGAGTTACTAGACCACCACCTCTTTTAAGTGAAGCTGACTTGCTTGGCTGTATGGACAAGGCTGGTATTGGTACGGATGCAACAATGCATGATCACATAAAGAAGTTGCTTGATCGATTCTATGCAACCAAGGACACAAGTACTCGTTTCTCACCAACTAATCTTGGTAAAGCTCTAGTTATGGGATATGATGACATGGGGTATGAGCTTTGGAAGCCAAATCTTAGATCAATGATGGAGTTTGACATGAAACAAGTTAGCATGGGTTATAAAAGTAAGGCTGAAGTTTTGGAAACTTGCTTGCAGCAGATGAAAAGTTGTTTCTTAGATGCAAGGGAAAATAAAGTAAAACTCCTAGAAGCCATGGCTGTTTTCTTTGAGAGATCGGATAGAATGAGTGGAAATGACCATCTTGTAGCTGTGGAAATTGTTCGGAAATGTGGACTTTGCCAAGAATCAAATATGGTGCTTAGACGAAATCGGGATGGCAATTTCATGGTTGGATGCTTGGGGTTTCCTCAGTGTAGGAATGCTATATGGCTTCCTGGACCTGTACTAGAGGCCACTGTAACCACCAACATTTGCAACAGTTGCACACCAGGTCCTGTTTACTTGATTCAATTTAAGTTTCGGCAGCTTGAAATACCACCAGGCTTCAATGTCAACCATTTAGGTTGCATTGGTGGCTGTGATGAGACTCTAAGACAGTTGATAGAGATATGCGGAACTGGTTCCCGCGTACAAGGGGAATCTTCAGTTTCATGTGGGACATGTGGAGAACCATGCTTTTTGCGTACAGCTAATACAGCAAATAACAGGGGAAGAAAGTTCTACTCATGTCCATCGCAAGGATGCAACTTCTTTGTATGGGAGGATAGCTTGAATAATGGCACCAATGGAAGAAATGCTCCCTACAGAAATGTTAGCAACTCGGCATCTAATCCTAGCAGAAGGGGTGGCCGTAGCAGAGGTGCACGGGGCGGTGGGACTTTTGTATCAGCCACTGGTGATCCCATATCTGGCAGAAGGTGTTACATATGCGGTGATCGATCTCACTTTGCAAATGCCTGTCCAATCTAA
Protein:  
MINVLNVAEKPSVAKSVATILSRNQQHGMRVRDGRSRYNKIFEFNYVINGQPCHMLVTSVTGHLMELEFEDRFRKWHSCDPTDLYHAPVRKFVPEDKIDIKRTLEEEARRCQWLILWLDCDREGENIAFEVMDVCGAANRHLTIWRARFSALIDREIHEAAQNLVSPNQWFSDAVDARQEIDLRIGASFTRFQTMLLRDKFVIGSAQDDRNLVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTINCSHTTDEGIATFSWMRGHLFDYTSAVILYEMCVQEPAATVTKVHQQEKRKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQAGFISYPRTETDGFSSRTDLHTIVREQQEHPVWGSYAQRLLDPGTGLWRNPSSGGHDDKAHPPIHPTKFSAGEIGWSQDHHRVYELVVRHFLACVSQPAVGAETIVEIDIAGEQFSASGRVILVKNYLDVYHFESWGGLMIPTYLQGQQFIPTTLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYATKDTSTRFSPTNLGKALVMGYDDMGYELWKPNLRSMMEFDMKQVSMGYKSKAEVLETCLQQMKSCFLDARENKVKLLEAMAVFFERSDRMSGNDHLVAVEIVRKCGLCQESNMVLRRNRDGNFMVGCLGFPQCRNAIWLPGPVLEATVTTNICNSCTPGPVYLIQFKFRQLEIPPGFNVNHLGCIGGCDETLRQLIEICGTGSRVQGESSVSCGTCGEPCFLRTANTANNRGRKFYSCPSQGCNFFVWEDSLNNGTNGRNAPYRNVSNSASNPSRRGGRSRGARGGGTFVSATGDPISGRRCYICGDRSHFANACPI